Link to online HCMV drug resitance mutations tool (UL54, UL97).
The details about the used protein sequences can be found here: Details about UL54 Details about UL97
Link to an online mutation resistence analyzer with support of wild bases and frameshift mutations
Just copy one of these sequences to the corresponding form field.
The sequence data must be submitted to the server by using the corresponding form field for UL54 or UL97. Important: the sequence is required in FASTA-Format. An optional identifier can be used to be shown in the result view. You can either copy the sequence in the text area or upload it in FASTA-format with a valid file extension (txt, fa, fasta).
The submitted data is compared via BLAST to the reference sequence of UL54 or UL97, respectively. Only sequences sharing more than 60 nucleotids with the reference sequence will be analysed. Access to the information is granted by a special id, so you can share your results with other users. Results can also be explicitly deleted in the result view.
Important: Everyone who may guess the id will have access to your results, so make sure not providing sensitive data e.g. name of patients.
In the result view mutations, insertions and deletions are listed in the upper area. Positions of mutations are visualized in the plotting area. If additional information about a mutation is found in our database, it is shown in the lower table.
You can permanently delete the results by clicking the "Delete" button on the top right of the result view. Otherwise, the results will be deleted after 7 days.
You can export the results in PDF-format by clicking the "Export" button on the top right of the result view.